Regulator of G-Protein Signaling 17 (RGS17) (C-Term) Peptide
RGS17
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN2184821
Aperçu rapide pour Regulator of G-Protein Signaling 17 (RGS17) (C-Term) Peptide (ABIN2184821)
Antigène
RGS17
(Regulator of G-Protein Signaling 17 (RGS17))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- NRNLLDPNPH MYEDAQLQIY TLMHRDSFPR FLNSQIYKSF VESTAGSSSE
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-RGS17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
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Sujet
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This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Alias Symbols: RGS-17, RGSZ2, hRGS17
Protein Size: 210 -
Poids moléculaire
- 23 kDa
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ID gène
- 26575
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NCBI Accession
- NM_012419, NP_036551
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UniProt
- Q9UGC6
Antigène
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